Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21734929 | 0.90 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735373 | 0.89 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735118 | 0.87 | CYP3A4 (0.33) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735075 | 0.81 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735229 | 0.81 | KDM4E (0.35) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735380 | 0.81 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21734968 | 0.81 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735268 | 0.80 | CYP3A4 (0.33) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL21735237 | 0.79 | HDAC6 (0.37) | CYP2C19CYP2C9KDM4EMEN1KMT2A | |
| SCHEMBL26291630 | 0.78 | APP (0.43) | CYP3A4CYP2C19CYP2E1CYP2D6CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | CYP3A4 1890/4885CYP2C19 1852/4885CYP2E1 3677/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | CYP3A4 1890/4885CYP2C19 1852/4885CYP2E1 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.