Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21736855 | 0.87 | KDM5A (0.39) | KDM5AKDM4CALDH1A1KDM4ELMNA | |
| SCHEMBL25732935 | 0.82 | CYP11B1 (0.36) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7215529 | 0.80 | KDM5A (0.39) | KDM5AKDM4CALDH1A1KDM4ELMNA | |
| SCHEMBL21736899 | 0.78 | PGK1 (0.37) | KDM5AKDM4CALDH1A1KDM4ELMNA | |
| SCHEMBL14822356 | 0.78 | CYP11B2 (0.39) | KDM5AKDM4CCYP11B1CYP11B2 | |
| SCHEMBL11154608 | 0.78 | NOS3 (0.38) | — | |
| SCHEMBL3559922 | 0.76 | TSHR (0.41) | ALDH1A1TSHRCYP11B1CYP11B2PRKCQ | |
| SCHEMBL10058048 | 0.76 | MEN1 (0.38) | KDM5AKDM4CALDH1A1KDM4ELMNA | |
| SCHEMBL15334774 | 0.75 | TSHR (0.44) | ALDH1A1TSHRCYP11B1CYP11B2PRKCQ | |
| SCHEMBL19779692 | 0.71 | TSHR (0.37) | KDM4ELMNAKMT2ATSHRCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |