Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24594988 | 0.79 | GAA (0.33) | PDE3BPDE3ATUBB1POLBGAA | |
| SCHEMBL9945896 | 0.77 | — | — | |
| SCHEMBL8885005 | 0.77 | TUBB1 (0.41) | TUBB1ACHECYP3A4LMNAMAPK1 | |
| SCHEMBL16133970 | 0.74 | PDE3B (0.43) | PDE3BPDE3APOLBGAAGFER | |
| SCHEMBL20226996 | 0.74 | ACHE (0.45) | PDE3BPDE3ATUBB1POLBGAA | |
| SCHEMBL27765600 | 0.74 | ALDH1A1 (0.38) | TUBB1POLBGAAACHECYP3A4 | |
| SCHEMBL16133964 | 0.73 | PDE3B (0.38) | PDE3BPDE3ATUBB1POLBGAA | |
| SCHEMBL13711373 | 0.72 | TUBB1 (0.38) | TUBB1POLBLMNAMAPK1HTT | |
| SCHEMBL13913528 | 0.72 | PDE3B (0.35) | PDE3BPDE3ATUBB1POLBGAA | |
| SCHEMBL27765697 | 0.72 | TUBB1 (0.36) | PDE3BPDE3ATUBB1POLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |