SCHEMBL21737529

SCHEMBL21737529

COc1c(C(C)C)csc1Br

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 2/20 0.36
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GFER P55789 1/20 0.32
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25128823 0.77 POLB (0.32) POLBGAAGFER
SCHEMBL25128822 0.77 KDM4E (0.31)
SCHEMBL19296841 0.75 MEN1 (0.33) NPC1RAB9APOLBGABRA1GABRB1
SCHEMBL10614301 0.75
SCHEMBL27838834 0.71 NPC1 (0.39) NPC1RAB9APOLBGAACA2
SCHEMBL3640929 0.71 GABRA1 (0.54) POLBGAAGABRA1GABRB1GFER
SCHEMBL2662645 0.71
SCHEMBL13919754 0.68 CA2 (0.35) NPC1RAB9APOLBGAACA2
SCHEMBL22711505 0.65 NPC1 (0.37) NPC1RAB9APOLBGAA
SCHEMBL13747710 0.65 GABRA1 (0.47) POLBGAAGABRA1GABRB1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed