Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747710 | 0.87 | GABRA1 (0.47) | GABRA1GABRB1POLBGAAGFER | |
| SCHEMBL282529 | 0.86 | GABRA1 (0.45) | GABRA1GABRB1POLBGAAGFER | |
| SCHEMBL10323552 | 0.84 | GABRA1 (0.40) | GABRA1GABRB1POLBGAAGFER | |
| SCHEMBL10323657 | 0.81 | ERN1 (0.47) | GABRA1GABRB1HSD17B10CA2 | |
| SCHEMBL11775737 | 0.78 | ACHE (0.48) | POLBGAAGFERCA2 | |
| SCHEMBL14640958 | 0.78 | GABRA1 (0.46) | GABRA1POLBGAAGFER | |
| SCHEMBL5002754 | 0.77 | CA2 (0.50) | GABRA1GABRB1POLBGAAGFER | |
| SCHEMBL11264823 | 0.77 | GABRA1 (0.50) | GABRA1GABRB1POLBHSD17B10 | |
| SCHEMBL14581607 | 0.77 | GABRA1 (0.45) | GABRA1GABRB1POLBGAAGFER | |
| SCHEMBL3817955 | 0.76 | GAA (0.42) | POLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613238-A | Preparation method of 2-bromo-1- (3, 5-diisopropyl- [1,1' -biphenyl ] -4-yl) -1H-benzo [ d ] imidazole | 浙江凯普化工有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-103896743-A | 2,6-diisopropyl-4-fluorophenol or salt and crystal form thereof as well as preparation method and application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2014-07-02 | — | — | CN | claimed |
| CN-119613238-A | Preparation method of 2-bromo-1- (3, 5-diisopropyl- [1,1' -biphenyl ] -4-yl) -1H-benzo [ d ] imidazole | 浙江凯普化工有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119613238-A | Preparation method of 2-bromo-1- (3, 5-diisopropyl- [1,1' -biphenyl ] -4-yl) -1H-benzo [ d ] imidazole | 浙江凯普化工有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-103896743-B | A kind of preparation method of 2,6 diisopropyl, 4 fluorophenol | 四川海思科制药有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-103896743-A | 2,6-diisopropyl-4-fluorophenol or salt and crystal form thereof as well as preparation method and application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2014-07-02 | — | — | CN | disclosed |
| EP-2155183-A1 | AMINO ACID DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals Ltd. (CA) | 2010-02-24 | — | — | EP | disclosed |
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
| WO-2008141446-A1 | AMINO ACID DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008141446-A1 | AMINO ACID DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-11-27 | — | — | WO | disclosed |
| EP-1077970-A1 | 11-ARYL-BENZO(B)NAPHTHO(2,3-D)FURANS AND 11-ARYL-BENZO(B)NAPHTHO(2,3-D)THIOPHENES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| US-6110962-A | FOR TREATING INSULIN RESISTANCE, TYPE II DIABETES, HYPERGLYCEMIA, MODULATING INSULIN LEVELS IN MAMMALS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1999058521-A1 | 11-ARYL-BENZO[B]NAPHTHO[2,3-D]FURANS AND 11-ARYL-BENZO[B]NAPHTHO[2,3-D]THIOPHENES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
| US-4361573-A | α,α-Diaryl-β-(tert-amino)-propanols and diuretic pharmaceutical compositions containing them | TEMMLER AG (CH) | 1982-11-30 | — | — | US | disclosed |
| US-4025633-A | DIURETICS, SALURETICS | FIRMA TEMMLER A.G. (CH) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | CACNA1G, CACNA1H, CACNA1I | GABRA1 135/4885GABRB1 109/4885POLB 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.