Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21738502 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL21738496 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL1373468 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL1373081 | 0.88 | ALDH1A1 (0.57) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL25715103 | 0.86 | KDM5A (0.39) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL1376896 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL26078816 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL1376984 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDCA2CA12CA9 | |
| SCHEMBL16355256 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HPGDCA2TSHRPOLB | |
| SCHEMBL1373604 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007275-B2 | Cryptophycin antibody conjugates for the treatment of cancer | SANOFI (FR) | 2021-05-18 | — | — | US | disclosed |
| US-20200054760-A1 | NOVEL PEPTIDIC LINKERS AND CRYPTOPHYCIN CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT (FR) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11007275-B2 | Cryptophycin antibody conjugates for the treatment of cancer | XPOT, CHMP4B, XPO5 | ALDH1A1 2273/4885HPGD 3640/4885CA2 1184/4885 |
| US-20200054760-A1 | NOVEL PEPTIDIC LINKERS AND CRYPTOPHYCIN CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | CLSPN, RPN1, MRPL37 | ALDH1A1 3013/4885HPGD 1494/4885CA2 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.