SCHEMBL2173936

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3124912	0.99	IDO1 (0.39)	IDO1NPFFR1NPFFR2DRD2CYP3A4
	SCHEMBL2151176	0.86	IDO1 (0.38)	IDO1NPFFR1NPFFR2DRD2CYP3A4
	SCHEMBL3131901	0.83	ROCK2 (0.36)	CYP3A4CYP2C19KMT2A
	SCHEMBL2209184	0.82	PDK2 (0.39)	DRD2CYP3A4CYP2C19NQO2
	SCHEMBL1725320	0.82	MALT1 (0.36)	IDO1DRD2CYP3A4CYP2C19MALT1
	SCHEMBL1726496	0.81	CYP3A4 (0.35)	IDO1DRD2CYP3A4CYP2C19MALT1
	SCHEMBL13323791	0.80	OPRK1 (0.42)	IDO1DRD2CA1CA2
	SCHEMBL611790	0.80	CYP3A4 (0.40)	IDO1NPFFR1NPFFR2DRD2CYP3A4
	SCHEMBL2178511	0.80	CA1 (0.40)	NPFFR1NPFFR2DRD2CYP3A4CYP2C19
	SCHEMBL2167735	0.80	CA1 (0.42)	IDO1CA1CA2MALT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.