Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 12/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21739672 | 0.79 | MTNR1A (0.34) | SMYD3 | |
| SCHEMBL21739657 | 0.78 | EPHX2 (0.40) | — | |
| SCHEMBL21739180 | 0.78 | SMYD3 (0.46) | SMYD3 | |
| SCHEMBL21739495 | 0.72 | SMYD3 (0.55) | SMYD3 | |
| SCHEMBL8326659 | 0.72 | KDM4E (0.45) | — | |
| SCHEMBL21740213 | 0.71 | MTNR1A (0.44) | SMYD3 | |
| SCHEMBL21739907 | 0.71 | SMYD3 (0.42) | SMYD3 | |
| SCHEMBL21739921 | 0.69 | EPHX1 (0.49) | — | |
| SCHEMBL21739422 | 0.69 | PTGES (0.42) | SMYD3 | |
| SCHEMBL19710084 | 0.68 | SMYD3 (0.60) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112872-A1 | METHODS OF TREATING WHSC1-OVEREXPRESSING CANCERS BY INHIBITING SETD2 | Epizyme, Inc. (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020037079-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |