Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565447 | 0.78 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL6583379 | 0.74 | ALDH1A1 (0.32) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL32677208 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL32677091 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL32676819 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL21739635 | 0.72 | SMYD3 (0.48) | — | |
| SCHEMBL29015454 | 0.72 | PDE5A (0.38) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL21739383 | 0.70 | KCNH2 (0.33) | ALDH1A1TSHRHTT | |
| SCHEMBL8301307 | 0.69 | HSD17B10 (0.39) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8745451 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |