Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22053077 | 0.86 | GFER (0.36) | GFERALDH1A1KMT2ARAB9A | |
| SCHEMBL21739728 | 0.85 | HRH4 (0.43) | GFERALDH1A1KMT2ARAB9A | |
| SCHEMBL21740173 | 0.83 | GAA (0.38) | GFERALDH1A1KMT2A | |
| SCHEMBL21740228 | 0.81 | PIM1 (0.37) | GFERALDH1A1MEN1KMT2A | |
| SCHEMBL21740347 | 0.81 | SMYD3 (0.50) | SMYD3NSD2SETD2 | |
| SCHEMBL21739140 | 0.79 | SMYD3 (0.46) | SMYD3NSD2SETD2 | |
| SCHEMBL21739129 | 0.79 | SMYD3 (0.43) | SMYD3NSD2SETD2 | |
| SCHEMBL21739138 | 0.79 | SMYD3 (0.43) | SMYD3NSD2SETD2 | |
| SCHEMBL21739718 | 0.78 | JAK1 (0.35) | GFERALDH1A1MEN1KMT2A | |
| SCHEMBL21740142 | 0.77 | SIGMAR1 (0.40) | SMYD3KDM5AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020037079-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |