Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21740228 | 0.85 | PIM1 (0.37) | GFERALDH1A1KMT2AEPHX2 | |
| SCHEMBL21739719 | 0.85 | SMYD3 (0.41) | GFERALDH1A1RAB9AKMT2A | |
| SCHEMBL22053077 | 0.84 | GFER (0.36) | GFERALDH1A1RAB9AKMT2AHCRTR1 | |
| SCHEMBL21739718 | 0.83 | JAK1 (0.35) | GFERALDH1A1KMT2AEPHX2 | |
| SCHEMBL21739194 | 0.77 | RIPK1 (0.48) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL21740219 | 0.76 | KMT2A (0.38) | ALDH1A1KMT2A | |
| SCHEMBL21740217 | 0.76 | ALDH1A1 (0.53) | GFERALDH1A1KMT2A | |
| SCHEMBL21739173 | 0.74 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL21739921 | 0.74 | EPHX1 (0.49) | RAB9AKMT2AEPHX2 | |
| SCHEMBL21739537 | 0.74 | KMT2A (0.31) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112872-A1 | METHODS OF TREATING WHSC1-OVEREXPRESSING CANCERS BY INHIBITING SETD2 | Epizyme, Inc. (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020037079-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |