Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | HRH1 | P35367 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428926 | 1.00 | HTR2A (0.61) | HTR2AHRH1TDP1CCR5SLC6A2 | |
| SCHEMBL21739938 | 1.00 | HTR2A (0.61) | HTR2AHRH1TDP1CCR5SLC6A2 | |
| SCHEMBL8754723 | 0.89 | HTR2A (0.70) | HTR2AHRH1TDP1CCR5SLC6A2 | |
| SCHEMBL169508 | 0.81 | LMNA (0.56) | HTR2AHRH1TDP1CCR5LMNA | |
| SCHEMBL7306592 | 0.81 | HTR2A (0.59) | HTR2AHRH1TDP1SLC6A2SLC6A4 | |
| SCHEMBL7306585 | 0.81 | HTR2A (0.59) | HTR2AHRH1TDP1SLC6A2SLC6A4 | |
| SCHEMBL9807100 | 0.81 | HTR2A (0.59) | HTR2AHRH1TDP1SLC6A2SLC6A4 | |
| SCHEMBL12712357 | 0.81 | HTR2A (0.59) | HTR2AHRH1TDP1CCR5SLC6A2 | |
| SCHEMBL9807099 | 0.81 | HTR2A (0.59) | HTR2AHRH1TDP1CCR5SLC6A2 | |
| SCHEMBL3425439 | 0.81 | CCR5 (0.53) | HTR2AHRH1TDP1CCR5SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261243-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2020037079-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |