SCHEMBL21740445

SCHEMBL21740445

c1ccc(-c2ccc3c4ccccc4n(-c4ccc5c(c4)oc4cc(-c6cccc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)c6)ccc45)c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGER4 P35408 1/20 0.33
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
PRKDC P78527 1/20 0.33
HDAC4 P56524 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
PGR P06401 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25954924 1.00 KDM4E (0.36) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL21669127 1.00 KDM4E (0.36) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL25954922 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL25954923 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL25954878 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL21883206 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL21740692 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL21740396 0.98 ATM (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL21668693 0.98 L3MBTL1 (0.37) KDM4EATML3MBTL1PTGER4MMP12
SCHEMBL22386974 0.97 PTGER4 (0.37) KDM4EATML3MBTL1PTGER4MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
EP-3611173-B1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT LT MATERIALS CO LTD (KR) 2021-07-28 EP disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2020-12-03 US disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed
EP-3611173-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM KDM4E 3489/4885ATM 2594/4885L3MBTL1 838/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM KDM4E 3489/4885ATM 2594/4885L3MBTL1 838/4885
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 KDM4E 2341/4885ATM 2995/4885L3MBTL1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.