SCHEMBL21740464

SCHEMBL21740464

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)oc3cc(-n5c6ccccc6c6c7oc8ccccc8c7ccc65)ccc34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
PTGER4 P35408 1/20 0.35
MAPT P10636 9/20 0.34
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 5/20 0.33
LMNA P02545 4/20 0.33
HSD17B10 Q99714 3/20 0.33
HPGD P15428 3/20 0.33
POLB P06746 2/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PRKDC P78527 1/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
AHR P35869 1/20 0.32
CYP3A4 P08684 2/20 0.32
ALPI P09923 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21740478 0.96 TSHR (0.33) TSHRPTGER4MAPTALDH1A1KDM4E
SCHEMBL21668946 0.96 ALDH1A1 (0.34) TSHRPTGER4MAPTALDH1A1KDM4E
SCHEMBL27444629 0.96 TSHR (0.35) TSHRPTGER4MAPTALDH1A1KDM4E
SCHEMBL27444641 0.95 KDM4E (0.36) TSHRMAPTALDH1A1KDM4ELMNA
SCHEMBL22240715 0.94 TSHR (0.34) TSHRMAPTALDH1A1KDM4ELMNA
SCHEMBL27444667 0.94 ALDH1A1 (0.35) TSHRMAPTALDH1A1KDM4ELMNA
SCHEMBL27444621 0.94 TSHR (0.31) TSHRALDH1A1KDM4EHSD17B10POLB
SCHEMBL27444597 0.94 ALDH1A1 (0.34) TSHRPTGER4MAPTALDH1A1KDM4E
SCHEMBL27444564 0.94 ALDH1A1 (0.34) TSHRPTGER4MAPTALDH1A1KDM4E
SCHEMBL25662513 0.93 TSHR (0.33) TSHRPTGER4MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-11-29 US disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
EP-3611173-B1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT LT MATERIALS CO LTD (KR) 2021-07-28 EP disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2020-12-03 US disclosed
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-08-20 US disclosed
EP-3683217-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd. (KR) 2020-07-22 EP disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed
EP-3611173-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 TSHR 4080/4885PTGER4 717/4885MAPT 1487/4885
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM TSHR 4716/4885PTGER4 1124/4885MAPT 1166/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM TSHR 4716/4885PTGER4 1124/4885MAPT 1166/4885
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 TSHR 4080/4885PTGER4 717/4885MAPT 1487/4885
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 TSHR 4080/4885PTGER4 717/4885MAPT 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.