SCHEMBL21741809

SCHEMBL21741809

COC1C(C)C2OC(C(C)C2C)C1O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349335 1.00 GBA1 (0.32) GBA1
SCHEMBL20349351 1.00 GBA1 (0.32) GBA1
SCHEMBL9973583 0.72
SCHEMBL19627514 0.70 FUCA1 (0.32)
SCHEMBL19277510 0.70 PPP5C (0.38)
SCHEMBL19277451 0.70 PPP5C (0.38)
SCHEMBL17525187 0.70 PPP5C (0.38)
SCHEMBL15086041 0.67 LMNA (0.39) GBA1
SCHEMBL19275879 0.67 GBA1 (0.47) GBA1
SCHEMBL21741986 0.67 GBA1 (0.47) GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10793581-B2 Stereochemically defined polypropionates and methods for making and using the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2020-10-06 US disclosed
US-20200055866-A1 STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055866-A1 STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME FDPS, DHPS, ADCYAP1R1 GBA1 1686/4885
US-10793581-B2 Stereochemically defined polypropionates and methods for making and using the same FDPS, DHPS, ADCYAP1R1 GBA1 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.