Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968807 | 0.83 | PARP1 (0.44) | DAOCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL18948019 | 0.82 | CYP1A2 (0.60) | DAOCYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL6468879 | 0.79 | CYP1A2 (0.48) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6027805 | 0.78 | CYP1A2 (0.64) | DAOCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL29654412 | 0.78 | PKM (0.42) | DAOCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL17501689 | 0.78 | PKM (0.42) | DAOCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL6294025 | 0.75 | PARP1 (0.46) | DAOCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL6028786 | 0.73 | PGR (0.60) | DAOPARP1ALDH1A1KDM4EHPGD | |
| SCHEMBL29528989 | 0.73 | PGR (0.60) | DAOPARP1ALDH1A1KDM4EHPGD | |
| SCHEMBL7750879 | 0.72 | PGR (0.55) | DAOPARP1ALDH1A1PARP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200056173-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-02-20 | — | — | US | disclosed |