Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.60 |
| ▸ | RORA | P35398 | 2/20 | 0.60 |
| ▸ | RORC | P51449 | 2/20 | 0.60 |
| ▸ | RORB | Q92753 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528989 | 1.00 | PGR (0.60) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL7750879 | 0.95 | PGR (0.55) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL10827376 | 0.84 | PARP1 (0.50) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL446902 | 0.84 | PARP1 (0.50) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL11009779 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TDP1PARP1HPGDLMNA | |
| SCHEMBL6295463 | 0.84 | PARP1 (0.50) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6027805 | 0.83 | CYP1A2 (0.64) | PGRALDH1A1PARP1KDM4EHPGD | |
| SCHEMBL7650175 | 0.83 | PARP1 (0.50) | ALDH1A1TDP1PARP1HPGDLMNA | |
| SCHEMBL7305582 | 0.83 | HTR1A (0.50) | ALDH1A1TDP1PARP1HPGDLMNA | |
| SCHEMBL7298333 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TDP1PARP1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207483-B | Alpha-amino-beta-carboxymuconate semialdehyde decarboxylase inhibitors | TES制药有限责任公司 | 2020-10-30 | — | — | CN | disclosed |
| US-7018786-B2 | Toning agents for use in thermographic recording materials | AGFA GEVAERT (BE) | 2006-03-28 | — | — | US | disclosed |