SCHEMBL21742474

SCHEMBL21742474

c1ccc(-c2cccc(-n3c4cc5c(cc4c4c6ccccc6ccc43)c3ccccc3n5-c3nc4ccccc4nc3-c3ccccc3)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DHODH Q02127 1/20 0.32
PTGES O14684 1/20 0.32
GSR P00390 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
NPY1R P25929 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168736 0.94 KDM4E (0.35) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168742 0.94 KDM4E (0.35) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168714 0.94 KDM4E (0.37) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168727 0.94 KDM4E (0.37) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL19507697 0.94 KDM4E (0.38) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL16838876 0.94 KDM4E (0.38) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL22479877 0.93 HSD17B10 (0.33) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168719 0.92 DHODH (0.35) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168732 0.91 HPGD (0.34) PDE10AKDM4EATML3MBTL1CASP1
SCHEMBL21168733 0.91 HPGD (0.34) PDE10AKDM4EATML3MBTL1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844269-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-12-12 US disclosed
US-11844269-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-12-12 US disclosed
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-20210193925-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210062081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-03-04 US disclosed
US-20210036239-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-02-04 US disclosed
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-09-24 US disclosed
US-20200119275-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-04-16 US disclosed
US-20200058882-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 PDE10A 3062/4885KDM4E 1410/4885ATM 2066/4885
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 PDE10A 3062/4885KDM4E 1410/4885ATM 2066/4885
US-20210193925-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, ICOSLG PDE10A 2966/4885KDM4E 1693/4885ATM 1793/4885
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 PDE10A 2552/4885KDM4E 684/4885ATM 2151/4885
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 PDE10A 3062/4885KDM4E 1410/4885ATM 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.