Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011136 | 0.91 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MEN1HSP90AA1 | |
| SCHEMBL14900744 | 0.89 | KDM4E (0.46) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL19011150 | 0.87 | KDM4E (0.51) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL21742511 | 0.86 | CHEK1 (0.41) | KDM4EL3MBTL1MKNK1MEN1MAPT | |
| SCHEMBL21742505 | 0.86 | ATM (0.38) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL21742841 | 0.85 | KDM4E (0.39) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL21742502 | 0.84 | JAK2 (0.35) | KDM4EATML3MBTL1MAPTNPC1 | |
| SCHEMBL21742639 | 0.82 | GRM5 (0.41) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL19933769 | 0.82 | KDM4E (0.56) | KDM4EATML3MBTL1MKNK1MEN1 | |
| SCHEMBL21742779 | 0.82 | L3MBTL1 (0.39) | KDM4EATML3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | KDM4E 3201/4885ATM 1504/4885L3MBTL1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.