Sugi Predict

Sugi Predict / Compounds / SCHEMBL19933769

SCHEMBL19933769

SCHEMBL19933769

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc(-c6ccncc6)ccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MKNK1 Q9BUB5 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ HSP90AA1 P07900 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PIK3CA P42336 1/20 0.43
▸ NOTUM Q6P988 1/20 0.42
▸ HTR6 P50406 3/20 0.41
▸ PTGER4 P35408 1/20 0.40
▸ MAPK14 Q16539 2/20 0.39
▸ TSPO P30536 1/20 0.39
▸ HDAC4 P56524 1/20 0.39
▸ DYRK1A Q13627 1/20 0.39
▸ IMPDH2 P12268 1/20 0.39
▸ SLC6A2 P23975 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ GRK2 P25098 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15371727 0.98 KDM4E (0.55) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL18717875 0.98 KDM4E (0.55) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL18790307 0.98 KDM4E (0.55) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL16291563 0.97 KDM4E (0.53) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL15371758 0.96 KDM4E (0.51) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL24526112 0.95 KDM4E (0.50) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL15371726 0.95 L3MBTL1 (0.58) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL17809411 0.95 L3MBTL1 (0.58) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL24493056 0.94 KDM4E (0.50) KDM4EATML3MBTL1MKNK1MEN1
SCHEMBL24526113 0.93 KDM4E (0.49) KDM4EATML3MBTL1MKNK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-14 — — US disclosed
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-14 — — US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 — — US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
WO-2020011686-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-01-16 — — WO disclosed
US-20200006687-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2020-01-02 — — US disclosed
WO-2019179909-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-09-26 — — WO disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 — — US disclosed
WO-2019158453-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-22 — — WO disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 — — US disclosed
WO-2019145316-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-08-01 — — WO disclosed
WO-2019115423-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-06-20 — — WO disclosed
WO-2018069196-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 — — WO disclosed
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 KDM4E 3877/4885ATM 4131/4885L3MBTL1 3031/4885
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 KDM4E 4613/4885ATM 4246/4885L3MBTL1 2504/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM KDM4E 2021/4885ATM 2990/4885L3MBTL1 1208/4885
US-20230271989-A1 METAL COMPLEXES AP3M1, AP1M1, AP2M1 KDM4E 3576/4885ATM 3098/4885L3MBTL1 2773/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.