Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.40 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173319 | 0.89 | MCHR1 (0.40) | MCHR1MCHR2HTR2CMAPK7 | |
| SCHEMBL5668886 | 0.83 | KMT2A (0.41) | MCHR1MCHR2HTR2C | |
| SCHEMBL5668892 | 0.80 | HPGD (0.40) | MCHR1GCGRHTR2C | |
| SCHEMBL5669978 | 0.78 | CHRM2 (0.43) | MCHR1 | |
| SCHEMBL4389385 | 0.77 | TAOK1 (0.43) | MCHR1 | |
| SCHEMBL2173905 | 0.77 | SHMT2 (0.43) | MCHR1 | |
| SCHEMBL2174025 | 0.76 | CHRM2 (0.41) | MCHR1 | |
| SCHEMBL5668246 | 0.76 | L3MBTL1 (0.49) | — | |
| SCHEMBL2172250 | 0.76 | MEN1 (0.45) | MCHR1 | |
| SCHEMBL4387610 | 0.75 | KDM4E (0.42) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973061-B2 | Anaplastic lymphoma kinase modulators and methods of use | EXELIXIS, INC. (US) | 2011-07-05 | — | — | US | disclosed |