SCHEMBL21742785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21742783	0.90	L3MBTL1 (0.44)	KDM4EL3MBTL1ATMCYP17A1CYP1A2
	SCHEMBL21742786	0.89	KDM4E (0.46)	KDM4EL3MBTL1ATMCYP17A1CYP1A2
	SCHEMBL27388107	0.89	KDM4E (0.46)	KDM4EL3MBTL1ATMCYP17A1CYP1A2
	SCHEMBL21742665	0.89	KDM4E (0.49)	KDM4EL3MBTL1ATMCYP17A1CYP1A2
	SCHEMBL18435975	0.86	L3MBTL1 (0.55)	KDM4EL3MBTL1ATMALKBH5FTO
	SCHEMBL14296001	0.86	L3MBTL1 (0.55)	KDM4EL3MBTL1ATMALKBH5FTO
	SCHEMBL14296000	0.86	L3MBTL1 (0.59)	KDM4EL3MBTL1ATMCYP17A1CYP1A2
	SCHEMBL16491724	0.86	L3MBTL1 (0.59)	KDM4EL3MBTL1ATMALKBH5FTO
	SCHEMBL19001662	0.85	NPC1 (0.50)	KDM4EL3MBTL1ATMDUSP3RXFP1
	SCHEMBL17879424	0.85	L3MBTL1 (0.50)	KDM4EL3MBTL1ATMALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.