Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742665 | 0.92 | KDM4E (0.49) | KDM4EL3MBTL1ATMHTR7HTR1A | |
| SCHEMBL14296001 | 0.91 | L3MBTL1 (0.55) | KDM4EL3MBTL1ATMALKBH5FTO | |
| SCHEMBL14296117 | 0.90 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMDUSP3KMT2A | |
| SCHEMBL14296102 | 0.90 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMDUSP3KMT2A | |
| SCHEMBL14296081 | 0.90 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMDUSP3KMT2A | |
| SCHEMBL21742785 | 0.89 | KDM4E (0.44) | KDM4EL3MBTL1ATMHTR7HTR1A | |
| SCHEMBL21742783 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMHTR7HTR1A | |
| SCHEMBL28194149 | 0.88 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMDUSP3KMT2A | |
| SCHEMBL14296125 | 0.88 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMDUSP3KMT2A | |
| SCHEMBL19001662 | 0.87 | NPC1 (0.50) | KDM4EL3MBTL1ATMDUSP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | KDM4E 3201/4885L3MBTL1 2878/4885ATM 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.