Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698323 | 0.91 | CYP2A6 (0.40) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL17426491 | 0.87 | KDM4E (0.52) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL18015186 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL18015184 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL18015355 | 0.84 | ALDH1A1 (0.54) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL19500912 | 0.83 | GRM5 (0.55) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL29679578 | 0.83 | KDM4E (0.62) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL502867 | 0.83 | KDM4E (0.62) | MAPK1ALDH1A1CYP2A6KDM4ELMNA | |
| SCHEMBL28673366 | 0.82 | MAPK1 (0.52) | MAPK1ALDH1A1CYP2A6GRM5TP53 | |
| SCHEMBL21506994 | 0.81 | KDM4E (0.59) | MAPK1ALDH1A1CYP2A6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | MAPK1 3046/4885ALDH1A1 323/4885CYP2A6 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.