Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021994 | 0.85 | KMT2A (0.70) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11196105 | 0.76 | NCF1 (0.83) | KMT2AALDH1A1KDM4EMEN1PARP1 | |
| SCHEMBL28158277 | 0.76 | SIGMAR1 (0.68) | KMT2AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL349204 | 0.76 | CHEK1 (0.53) | ALDH1A1MAPTPARP1NPC1RAB9A | |
| SCHEMBL4106102 | 0.76 | ALDH1A1 (0.68) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL15467001 | 0.75 | HRH3 (0.87) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL348688 | 0.75 | PARP1 (0.45) | ALDH1A1KDM4EPARP1NPC1RAB9A | |
| SCHEMBL9986621 | 0.75 | TP53 (0.73) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL5168930 | 0.75 | NPC1 (0.57) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL5017070 | 0.74 | NPC1 (0.57) | KMT2AALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200056181-A1 | Aptamers to PDGF and VEGF and Their Use in Treating PDGF and VEGF Mediated Conditions | SOMALOGIC OPERATING CO., INC. | 2020-02-20 | — | — | US | disclosed |