Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327372 | 0.79 | EPAS1 (0.55) | EPAS1PTGS2PTGS1SLC22A12 | |
| SCHEMBL2888292 | 0.76 | EPAS1 (0.51) | EPAS1PTGS2PTGS1SLC22A12 | |
| SCHEMBL4064154 | 0.75 | EPAS1 (0.46) | EPAS1PTGS2PTGS1SLC22A12 | |
| SCHEMBL13448493 | 0.74 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL21743211 | 0.74 | RORC (0.38) | PTGS2SCN9ASLC22A12 | |
| SCHEMBL4935434 | 0.73 | LMNA (0.53) | PTGS2PTGS1 | |
| SCHEMBL10051874 | 0.73 | EPAS1 (0.55) | EPAS1PTGS2PTGS1 | |
| SCHEMBL21116203 | 0.73 | USP8 (0.42) | — | |
| SCHEMBL31245792 | 0.73 | PSEN1 (0.43) | PTGS2PTGS1SCN9A | |
| SCHEMBL21743184 | 0.73 | PSEN1 (0.43) | PTGS2PTGS1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035560-A1 | 1-METHYL-4-[(4-PHENYLPHENYL)SULFONYLMETHYL]CYCLOHEXYANOL AND 1-METHYL-4-[[4-(2-PYRIDYL)PHENYL]SULFONYLMETHYL]CYCLOHEXANOL COMPOUNDS AND THEIR THERAPEUTIC USE | Modern Biosciences Limited (GB) | 2020-02-20 | — | — | WO | disclosed |