SCHEMBL21743205

SCHEMBL21743205

NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1c[nH]c2ccccc12)NC=O

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 6/20 0.65
GHSR Q92847 3/20 0.62
OPRM1 P35372 1/20 0.62
ACE P12821 2/20 0.56
HPGDS O60760 2/20 0.55
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14599288 0.95 ECE1 (0.59) ECE1GHSROPRM1
SCHEMBL7326281 0.92 GHSR (0.59) ECE1GHSROPRM1ACEHPGDS
SCHEMBL24122578 0.90 ECE1 (0.67) ECE1GHSROPRM1ACEHPGDS
SCHEMBL25093063 0.90 ECE1 (0.56) ECE1GHSROPRM1ACE
SCHEMBL14446365 0.88 ACE (0.59) ECE1GHSROPRM1ACEALOX15
SCHEMBL14446078 0.88 ACE (0.59) ECE1GHSROPRM1ACEALOX15
SCHEMBL21862858 0.86 ECE1 (0.51) ECE1GHSROPRM1ACEHPGDS
SCHEMBL19929604 0.85 ECE1 (0.77) ECE1ACEHPGDS
SCHEMBL23266831 0.85 GHSR (0.56) ECE1GHSROPRM1ACEALOX15
SCHEMBL24122594 0.85 ECE1 (0.69) ECE1GHSRACEALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022266340-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES FOR DRUG DELIVERY APPLICATIONS VACCITECH NORTH AMERICA, INC. (US) 2022-12-22 WO disclosed
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE AVIDEA TECHNOLOGIES, INC. (US) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE MYD88, ICOS, CD4 ECE1 3131/4885GHSR 2065/4885OPRM1 4680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.