Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MC5R | P33032 | 2/20 | 0.53 |
| ▸ | MC1R | Q01726 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743205 | 0.92 | ECE1 (0.65) | GHSROPRM1ECE1ALOX15HPGDS | |
| SCHEMBL24425711 | 0.90 | ALOX15 (0.62) | GHSROPRM1ECE1ALOX15KDM4E | |
| SCHEMBL29402200 | 0.88 | ALOX15 (0.67) | ECE1ALOX15KDM4EMAPTMEN1 | |
| SCHEMBL5519036 | 0.88 | ALOX15 (0.67) | ECE1ALOX15KDM4EMAPTMEN1 | |
| SCHEMBL120493 | 0.88 | ALOX15 (0.67) | ECE1ALOX15KDM4EMAPTMEN1 | |
| SCHEMBL120495 | 0.88 | ALOX15 (0.67) | ECE1ALOX15KDM4EMAPTMEN1 | |
| SCHEMBL14599288 | 0.87 | ECE1 (0.59) | GHSROPRM1ECE1 | |
| SCHEMBL24122578 | 0.86 | ECE1 (0.67) | GHSROPRM1ECE1ALOX15HPGDS | |
| SCHEMBL9845636 | 0.86 | GHSR (0.55) | GHSROPRM1ALOX15KDM4EMAPT | |
| SCHEMBL23266831 | 0.86 | GHSR (0.56) | GHSROPRM1ECE1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203031-A2 | Biologically active lysine containing octapeptides | The Administrators of The Tulane University Educational Fund (US) | 1986-11-26 | — | — | EP | claimed |
| US-20220096646-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2022-03-31 | — | — | US | disclosed |
| EP-3916003-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | Naurex, Inc. (US) | 2021-12-01 | — | — | EP | disclosed |
| US-11160871-B2 | SSTR-targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200206356-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2020-07-02 | — | — | US | disclosed |
| US-10624967-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-10322191-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180221499-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2018-08-09 | — | — | US | disclosed |
| US-20170312245-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-11-02 | — | — | US | disclosed |
| US-9750818-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| US-20170095569-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-04-06 | — | — | US | disclosed |
| US-4725577-A | Biologically active lysine containing octapeptides | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1988-02-16 | — | — | US | disclosed |
| US-4650787-A | SOMATOSTATIN ANALOG | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND OF NEW ORLEANS, LOUISIANA, THE, | 1987-03-17 | — | — | US | disclosed |
| EP-0203031-A2 | Biologically active lysine containing octapeptides | The Administrators of The Tulane University Educational Fund (US) | 1986-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624967-B2 | Targeted conjugates and particles and formulations thereof | SSTR5, SSTR1, SSTR4 | GHSR 19/4885OPRM1 2036/4885ECE1 829/4885 |
| US-20220096646-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | SSTR1, SSTR4, SSTR3 | GHSR 13/4885OPRM1 1258/4885ECE1 2202/4885 |
| US-20200206356-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | SSTR5, SSTR1, SSTR4 | GHSR 19/4885OPRM1 2036/4885ECE1 829/4885 |
| US-20180221499-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | SSTR1, SSTR4, SSTR3 | GHSR 13/4885OPRM1 1258/4885ECE1 2202/4885 |
| US-20170095569-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | SSTR5, SSTR1, SSTR4 | GHSR 19/4885OPRM1 2036/4885ECE1 829/4885 |
| US-10322191-B2 | Targeted conjugates and particles and formulations thereof | SSTR5, SSTR1, SSTR4 | GHSR 19/4885OPRM1 2036/4885ECE1 829/4885 |
| US-11160871-B2 | SSTR-targeted conjugates and particles and formulations thereof | SSTR1, SSTR4, SSTR3 | GHSR 13/4885OPRM1 1258/4885ECE1 2202/4885 |
| US-20170312245-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | SSTR5, SSTR1, SSTR4 | GHSR 19/4885OPRM1 2036/4885ECE1 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.