Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.56 |
| ▸ | GHSR | Q92847 | 4/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.53 |
| ▸ | IL1RN | P18510 | 2/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
| ▸ | NPY4R | P50391 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743205 | 0.90 | ECE1 (0.65) | ECE1GHSROPRM1ACE | |
| SCHEMBL14599288 | 0.87 | ECE1 (0.59) | ECE1GHSROPRM1MMP2MMP9 | |
| SCHEMBL7326281 | 0.84 | GHSR (0.59) | ECE1GHSROPRM1ERAP2ACE | |
| SCHEMBL30291306 | 0.83 | ECE1 (0.61) | ECE1GHSRERAP2IL1RNERAP1 | |
| SCHEMBL24122578 | 0.83 | ECE1 (0.67) | ECE1GHSROPRM1ERAP2IL1RN | |
| SCHEMBL24024006 | 0.82 | MEN1 (0.62) | ECE1ERAP2ACECCKBR | |
| SCHEMBL21985036 | 0.82 | GHSR (0.56) | ECE1GHSROPRM1ACE | |
| SCHEMBL31666000 | 0.81 | ERAP2 (0.58) | ECE1GHSRERAP2NPY1RNPY2R | |
| SCHEMBL30291296 | 0.81 | ERAP2 (0.58) | ECE1GHSRERAP2NPY1RNPY2R | |
| SCHEMBL29886842 | 0.81 | ERAP2 (0.58) | ECE1GHSRERAP2NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4140542-A1 | NEW VASHS INHIBITORS, CONJUGATES THEREOF AND THEIR USES AS DRUGS OR AS RESEARCH TOOLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2023-03-01 | — | — | EP | disclosed |