Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 19/20 | 0.82 |
| ▸ | CSF1R | P07333 | 16/20 | 0.82 |
| ▸ | KDR | P35968 | 15/20 | 0.82 |
| ▸ | FLT3 | P36888 | 8/20 | 0.82 |
| ▸ | MET | P08581 | 2/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174542 | 0.83 | PDGFRB (0.84) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598739 | 0.80 | PDGFRB (0.74) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2172536 | 0.78 | KDR (0.81) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL4214384 | 0.76 | PDGFRB (0.77) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2174490 | 0.75 | PDGFRB (0.69) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2173785 | 0.74 | PDGFRB (0.77) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598429 | 0.74 | PDGFRB (0.65) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2172612 | 0.74 | PDGFRB (0.74) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2172911 | 0.73 | PDGFRB (1.00) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2176706 | 0.73 | PDGFRB (0.83) | PDGFRBCSF1RKDRFLT3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973164-B2 | Quinoline derivatives | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | claimed |