Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21746093 | 0.80 | LMNA (0.33) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL21746022 | 0.79 | KDM4E (0.47) | EDNRALMNASMN1; SMN2 | |
| SCHEMBL1858705 | 0.66 | — | — | |
| SCHEMBL16430495 | 0.65 | EDNRA (0.32) | EDNRA | |
| SCHEMBL13356959 | 0.64 | IDH1 (0.44) | — | |
| SCHEMBL21746025 | 0.63 | EDNRA (0.34) | EDNRA | |
| SCHEMBL29451087 | 0.63 | — | — | |
| SCHEMBL610831 | 0.63 | — | — | |
| SCHEMBL3132342 | 0.62 | NNMT (0.59) | SMN1; SMN2 | |
| SCHEMBL4978865 | 0.60 | CA2 (0.61) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |