Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174877 | 0.86 | TYR (0.46) | TYRKMT2AGAAMEN1MAPT | |
| SCHEMBL19713102 | 0.82 | TYR (0.49) | TYRCA1CA2TSHRGAA | |
| SCHEMBL19713095 | 0.82 | TYR (0.49) | TYRCA1CA2TSHRGAA | |
| SCHEMBL7463502 | 0.80 | MAOB (0.42) | GFERMAOBCA1CA2TP53 | |
| SCHEMBL5490550 | 0.80 | ALDH1A1 (0.43) | TYRMAOBCA1CA2TP53 | |
| SCHEMBL4070600 | 0.80 | BCHE (0.52) | TYRMAOBTSHRKMT2AGAA | |
| SCHEMBL23922718 | 0.78 | TYR (0.60) | NR1H4TTRTYRGFERMAOB | |
| SCHEMBL29492399 | 0.78 | TYR (0.60) | NR1H4TTRTYRGFERMAOB | |
| SCHEMBL3955351 | 0.77 | MEN1 (0.51) | TYRTP53KMT2AMEN1MAPT | |
| SCHEMBL4686426 | 0.76 | TYR (0.57) | TYRCA1CA2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346844-A1 | SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS | Council Of Scientific & Industrial Research (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010052734-A1 | SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-05-14 | — | — | WO | disclosed |