Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070600 | 0.92 | BCHE (0.52) | ALDH1A1CYP3A4KMT2AMEN1HPGD | |
| SCHEMBL4684702 | 0.84 | ACHE (0.45) | ALDH1A1KMT2AMEN1TP53MAPT | |
| SCHEMBL3955351 | 0.83 | MEN1 (0.51) | ALDH1A1CYP3A4KMT2AMEN1TP53 | |
| SCHEMBL4661084 | 0.82 | TYR (0.65) | ALDH1A1CYP3A4MAPTHPGDTDP1 | |
| SCHEMBL22365701 | 0.82 | TYR (0.65) | ALDH1A1CYP3A4MAPTHPGDTDP1 | |
| SCHEMBL14156960 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1TP53MAPT | |
| SCHEMBL5493143 | 0.81 | TSHR (0.40) | ALDH1A1CYP3A4KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL1010039 | 0.81 | HSP90AA1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL2827168 | 0.80 | TYR (0.43) | ALDH1A1MAPTHPGDTYRMAOB | |
| SCHEMBL2174674 | 0.80 | NR1H4 (0.45) | KMT2AMEN1TP53MAPTTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861402-A1 | ISOFLAVONOID DIMERS | Novogen Research Pty. Ltd. (AU) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099681-A1 | ISOFLAVONOID DIMERS | NOVOGEN RESEARCH PTY LTD (AU) | 2006-09-28 | — | — | WO | disclosed |