SCHEMBL21746799

SCHEMBL21746799

CN/C=C(/Br)C(=N)N1CCCOC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21746015 0.81 F2 (0.32)
SCHEMBL21746006 0.81
SCHEMBL21746579 0.80 LMNA (0.35) ALDH1A1HPGDTSHR
SCHEMBL21746010 0.80 F2 (0.35) ALDH1A1
SCHEMBL21746797 0.72 ALDH1A1 (0.33) ALDH1A1HPGDTSHR
SCHEMBL21746793 0.70
SCHEMBL21746803 0.69
SCHEMBL21746671 0.65
SCHEMBL25075684 0.60
SCHEMBL14595642 0.60 PDK1 (0.46) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2944637-B1 NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF FUJIFILM CORP (JP) 2020-02-19 EP disclosed