SCHEMBL21746808

SCHEMBL21746808

CSNc1ccc(N)nn1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10269008 0.75
SCHEMBL21746090 0.74 GAA (0.54) ALDH1A1GAAMAPT
SCHEMBL21746025 0.74 EDNRA (0.34)
Hydrochloric Acid SCHEMBL11638007 0.73 NCF1 (0.35) BCAT2ALDH1A1GAAMAPT
SCHEMBL9805068 0.72
SCHEMBL10212536 0.70 HCAR3 (0.38) BCAT2ALDH1A1GAAMAPT
SCHEMBL1255843 0.69
SCHEMBL31490392 0.69
SCHEMBL17247583 0.67 LMNA (0.41) ALDH1A1GAA
SCHEMBL4889623 0.67 HCAR3 (0.41) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2944637-B1 NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF FUJIFILM CORP (JP) 2020-02-19 EP disclosed