Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21747452 | 0.99 | HSD17B10 (0.49) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL21747471 | 0.91 | HDAC1 (0.50) | HSD17B10HDAC6MAPTRXFP1HDAC1 | |
| SCHEMBL21747446 | 0.91 | TP53 (0.49) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL21747472 | 0.90 | SIRT1 (0.49) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL30468251 | 0.88 | HDAC6 (0.47) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL21747460 | 0.88 | HDAC6 (0.47) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL30468220 | 0.88 | HSD17B10 (0.44) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL21747443 | 0.85 | HSD17B10 (0.58) | HSD17B10TP53NPC1RAB9AKMT2A | |
| SCHEMBL21747442 | 0.83 | SIRT1 (0.52) | HSD17B10HDAC6HDAC1LMNAABCB1 | |
| SCHEMBL21747469 | 0.82 | HSD17B10 (0.48) | HSD17B10NPC1RAB9ABCHEHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | claimed |
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |