Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747469 | 0.92 | HSD17B10 (0.48) | HSD17B10BCHENPC1RAB9AHDAC6 | |
| SCHEMBL21747448 | 0.91 | HSD17B10 (0.49) | TP53HSD17B10BCHENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21747452 | 0.90 | HSD17B10 (0.49) | TP53HSD17B10BCHENPC1RAB9A | |
| SCHEMBL21747472 | 0.89 | SIRT1 (0.49) | TP53HSD17B10BCHENPC1RAB9A | |
| SCHEMBL30468220 | 0.88 | HSD17B10 (0.44) | TP53HSD17B10BCHENPC1RAB9A | |
| SCHEMBL21747460 | 0.87 | HDAC6 (0.47) | TP53HSD17B10BCHENPC1RAB9A | |
| SCHEMBL30468251 | 0.87 | HDAC6 (0.47) | TP53HSD17B10BCHENPC1RAB9A | |
| SCHEMBL21747494 | 0.85 | HSD17B10 (0.57) | TP53HSD17B10NPC1RAB9AKMT2A | |
| SCHEMBL20541736 | 0.84 | NPC1 (0.49) | BCHENPC1RAB9AKMT2AFAAH | |
| SCHEMBL21747477 | 0.84 | SIRT1 (0.51) | TP53HSD17B10BCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |