Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747446 | 0.92 | TP53 (0.49) | HSD17B10S1PR1S1PR3HDAC6MAPT | |
| SCHEMBL21747471 | 0.91 | HDAC1 (0.50) | HSD17B10S1PR1S1PR3HDAC6CDK2 | |
| SCHEMBL21747493 | 0.89 | SIRT1 (0.51) | HSD17B10S1PR1S1PR3HDAC6CDK2 | |
| SCHEMBL21747494 | 0.89 | HSD17B10 (0.57) | HSD17B10MAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL30468309 | 0.88 | GPR119 (0.45) | HSD17B10S1PR1S1PR3HDAC6CDK2 | |
| SCHEMBL21747477 | 0.87 | SIRT1 (0.51) | HSD17B10S1PR1S1PR3HDAC6KDM4E | |
| SCHEMBL21747487 | 0.87 | PDCD1 (0.47) | HSD17B10S1PR1S1PR3HDAC6CDK2 | |
| SCHEMBL21747444 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3HDAC6PDCD1CD274 | |
| SCHEMBL21747448 | 0.82 | HSD17B10 (0.49) | HSD17B10HDAC6MAPTKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL21747452 | 0.82 | HSD17B10 (0.49) | HSD17B10HDAC6MAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |