Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541721 | 0.90 | KDM4E (0.52) | KDM4EUSP2ALDH1A1LMNAALOX15 | |
| SCHEMBL20541856 | 0.89 | BCHE (0.43) | BACE1KDM4EALDH1A1BCHEDRD4 | |
| SCHEMBL20541987 | 0.89 | S1PR1 (0.47) | BACE1KDM4EALDH1A1BCHEDRD4 | |
| SCHEMBL20542016 | 0.89 | BACE1 (0.44) | BACE1KDM4EALDH1A1BCHEDRD4 | |
| SCHEMBL21747496 | 0.89 | FAAH (0.44) | BACE1LMNABCHEDRD4FAAH | |
| SCHEMBL30468295 | 0.88 | BACE1 (0.53) | BACE1KDM4EBCHEDRD4MEN1 | |
| Hydrochloric Acid SCHEMBL20541653 | 0.88 | BACE1 (0.46) | BACE1BCHEDRD4 | |
| SCHEMBL20542002 | 0.88 | MCHR1 (0.45) | ALDH1A1HSD17B10DRD4MEN1KMT2A | |
| SCHEMBL20541736 | 0.86 | NPC1 (0.49) | BCHEDRD4KMT2AFAAH | |
| SCHEMBL20541911 | 0.85 | SLC6A12 (0.47) | BACE1KDM4EALDH1A1MAPK1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |