Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.44 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541987 | 0.90 | S1PR1 (0.47) | BACE1FAAHBCHES1PR1S1PR3 | |
| SCHEMBL20541856 | 0.90 | BCHE (0.43) | BACE1FAAHBCHES1PR1S1PR3 | |
| SCHEMBL21747496 | 0.90 | FAAH (0.44) | BACE1FAAHBCHES1PR1S1PR3 | |
| SCHEMBL21747485 | 0.89 | BACE1 (0.49) | BACE1FAAHBCHEDRD4KDM4E | |
| SCHEMBL20542002 | 0.88 | MCHR1 (0.45) | FAAHS1PR1S1PR3DRD4MEN1 | |
| SCHEMBL30468259 | 0.88 | BACE1 (0.46) | BACE1FAAHBCHEMAPK8 | |
| Hydrochloric Acid SCHEMBL21747476 | 0.88 | SIRT1 (0.45) | BACE1BCHES1PR1S1PR3KDM4E | |
| SCHEMBL20541734 | 0.88 | FAAH (0.44) | BACE1FAAHBCHES1PR1S1PR3 | |
| SCHEMBL20541911 | 0.86 | SLC6A12 (0.47) | BACE1FAAHBCHES1PR1S1PR3 | |
| SCHEMBL20541985 | 0.85 | HDAC1 (0.49) | BACE1FAAHS1PR1S1PR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018194372-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | 부산대학교 산학협력단 | 2018-10-25 | — | — | WO | disclosed |