Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049968 | 0.83 | CES1 (0.44) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28944445 | 0.81 | NPSR1 (0.49) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL9437357 | 0.80 | PIN1 (0.53) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL7616395 | 0.79 | ALDH1A1 (0.48) | PIN1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28653958 | 0.79 | ALDH1A1 (0.50) | NPSR1PIN1LMNAALDH1A1MEN1 | |
| SCHEMBL29256551 | 0.78 | ALDH1A1 (0.54) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL9437333 | 0.78 | MEN1 (0.51) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL28458817 | 0.78 | SRC (0.66) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL4621876 | 0.78 | PIN1 (0.51) | NPSR1POLBPIN1LMNAALDH1A1 | |
| SCHEMBL8679766 | 0.78 | PIN1 (0.51) | NPSR1POLBPIN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613733-B1 | NOVEL CRYSTALLINE SOLID COMPOUND OF 3-PHENYL-4-PROPYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-OL HYDROCHLORIDE | APTABIO THERAPEUTICS INC (KR) | 2022-07-20 | — | — | EP | disclosed |
| US-11174240-B2 | Crystalline solid compound of 3-phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol hydrochloride | APTABIO THERAPEUTICS INC. (KR) | 2021-11-16 | — | — | US | disclosed |
| US-20210122726-A1 | NOVEL CRYSTALLINE SOLID COMPOUND OF 3-PHENYL-4-PROPYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-OL HYDROCHLORIDE | APTABIO THERAPEUTICS INC. (KR) | 2021-04-29 | — | — | US | disclosed |
| EP-3613733-A1 | NOVEL CRYSTALLINE SOLID COMPOUND OF 3-PHENYL-4-PROPYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-OL HYDROCHLORIDE | Aptabio Therapeutics Inc. (KR) | 2020-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122726-A1 | NOVEL CRYSTALLINE SOLID COMPOUND OF 3-PHENYL-4-PROPYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-OL HYDROCHLORIDE | PLK3, PDXK, KLK5 | NPSR1 3292/4885POLB 2700/4885PIN1 2694/4885 |
| US-11174240-B2 | Crystalline solid compound of 3-phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol hydrochloride | PLK3, PRNP, PDXK | NPSR1 3177/4885POLB 3017/4885PIN1 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.