Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20502815 | 0.91 | L3MBTL1 (0.39) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21800623 | 0.87 | APP (0.37) | KMT2AMEN1RAB9AMMP2ADAM17 | |
| SCHEMBL21749194 | 0.83 | L3MBTL1 (0.45) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21749211 | 0.83 | L3MBTL1 (0.45) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2888789 | 0.83 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL22981673 | 0.82 | KMT2A (0.52) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3497808 | 0.82 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21749176 | 0.82 | L3MBTL1 (0.46) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21749162 | 0.81 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL20503060 | 0.81 | L3MBTL1 (0.45) | L3MBTL1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10960007-B2 | Pharmacologically active aryl-substituted pyrazolo[1,5-a]pyrimidine derivatives | RICHTER GEDEON NYRT. (HU) | 2021-03-30 | — | — | US | disclosed |
| US-20200061068-A1 | Pharmacologically Active Aryl-Substituted Pyrazolo[1,5-a]Pyrimidine Derivatives | RICHTER GEDEON NYRT. (HU) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200061068-A1 | Pharmacologically Active Aryl-Substituted Pyrazolo[1,5-a]Pyrimidine Derivatives | GABRA5, P2RX5, P2RY1 | L3MBTL1 4778/4885KMT2A 3817/4885MEN1 4170/4885 |
| US-10960007-B2 | Pharmacologically active aryl-substituted pyrazolo[1,5-a]pyrimidine derivatives | GABRA5, P2RX5, P2RY1 | L3MBTL1 4778/4885KMT2A 3817/4885MEN1 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.