Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750116 | 0.90 | EGLN1 (0.38) | RORCKDM4EDDR1PTGER4 | |
| SCHEMBL30423857 | 0.90 | EGLN1 (0.38) | RORCKDM4EDDR1PTGER4 | |
| SCHEMBL30423852 | 0.89 | JAK2 (0.39) | RORCDDR1PTGER4CNR2 | |
| SCHEMBL21750126 | 0.89 | DDR1 (0.35) | RORCDDR1CNR2 | |
| SCHEMBL21750109 | 0.89 | JAK2 (0.39) | RORCDDR1PTGER4CNR2 | |
| SCHEMBL30424023 | 0.89 | DDR1 (0.35) | RORCDDR1CNR2 | |
| SCHEMBL21750099 | 0.87 | RORC (0.33) | RORCDDR1CNR2 | |
| SCHEMBL21750114 | 0.86 | RORC (0.32) | RORCDDR1 | |
| SCHEMBL17514096 | 0.86 | CNR2 (0.32) | RORCDDR1LRRK2CNR2NPC1 | |
| SCHEMBL21761671 | 0.85 | EGLN1 (0.32) | RORCDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-19 | — | — | US | disclosed |
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-19 | — | — | US | disclosed |
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (IN) | 2020-02-27 | — | — | US | disclosed |
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (IN) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | RORC 1986/4885KDM4E 3259/4885DDR1 4585/4885 |
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | RORC 1986/4885KDM4E 3259/4885DDR1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.