Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750120 | 0.95 | POLB (0.44) | POLBEGLN1RORCDDR1ALDH1A1 | |
| SCHEMBL21750131 | 0.92 | POLB (0.44) | POLBEGLN1RORCDDR1ALDH1A1 | |
| SCHEMBL17329179 | 0.87 | POLB (0.47) | POLBEGLN1RORCDDR1ALDH1A1 | |
| SCHEMBL15947510 | 0.87 | POLB (0.47) | POLBEGLN1RORCDDR1 | |
| SCHEMBL21750121 | 0.87 | RORC (0.30) | POLBRORC | |
| SCHEMBL15947554 | 0.86 | POLB (0.46) | POLBEGLN1RORCDDR1ALDH1A1 | |
| SCHEMBL14684583 | 0.85 | POLB (0.48) | POLBEGLN1DDR1ALDH1A1 | |
| SCHEMBL29360277 | 0.85 | POLB (0.48) | POLBEGLN1DDR1ALDH1A1 | |
| SCHEMBL17329177 | 0.85 | POLB (0.52) | POLBALDH1A1GAA | |
| SCHEMBL15947552 | 0.85 | POLB (0.45) | POLBEGLN1RORCDDR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-19 | — | — | US | disclosed |
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-19 | — | — | US | disclosed |
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (IN) | 2020-02-27 | — | — | US | disclosed |
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (IN) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062755-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | POLB 4005/4885EGLN1 3702/4885RORC 1986/4885 |
| US-10894792-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | POLB 4005/4885EGLN1 3702/4885RORC 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.