Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763797 | 0.75 | IDH2 (0.35) | TSHRIDH2ALDH1A1POLBHTT | |
| SCHEMBL21751246 | 0.72 | IDH2 (0.36) | TSHRIDH2ALDH1A1POLBHTT | |
| SCHEMBL21763694 | 0.68 | KDM4E (0.50) | TSHRALDH1A1HTTMAPK1NPSR1 | |
| SCHEMBL28659747 | 0.67 | CCR4 (0.31) | IDH2 | |
| SCHEMBL21763693 | 0.66 | GRM4 (0.47) | ALDH1A1POLBTP53GAALMNA | |
| SCHEMBL21751257 | 0.66 | KDM4E (0.37) | GAA | |
| SCHEMBL21751258 | 0.65 | KDM4E (0.34) | TSHRNPSR1 | |
| SCHEMBL12300309 | 0.63 | L3MBTL1 (0.42) | TSHRALDH1A1HTTMAPK1GAA | |
| SCHEMBL2702752 | 0.60 | ALOX15 (0.33) | ALDH1A1 | |
| SCHEMBL18827776 | 0.60 | LOXL2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200060276-A1 | THIAZOLE COMPOUND AND HERBICIDE | OAT AGRIO CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| US-20200060276-A1 | THIAZOLE COMPOUND AND HERBICIDE | OAT AGRIO CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200060276-A1 | THIAZOLE COMPOUND AND HERBICIDE | OR10J3, OXSR1, OXER1 | TSHR 5/4885IDH2 191/4885ALDH1A1 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.