SCHEMBL21752785

SCHEMBL21752785

c1ccc(-c2nc3ccccc3s2)c(O[Zn]Oc2ccccc2-c2nc3ccccc3s2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
NPC1 O15118 6/20 0.58
RAB9A P51151 6/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
KDM4E B2RXH2 8/20 0.58
MAPT P10636 4/20 0.58
GAA P10253 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
GLA P06280 2/20 0.55
HCRTR1 O43613 1/20 0.55
ILK Q13418 2/20 0.50
LMNA P02545 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PKM P14618 1/20 0.50
APP P05067 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25068629 0.86 KDM4E (0.62) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL21131752 0.83 KDM4E (0.63) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL2088159 0.83 ALDH1A1 (0.76) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL30161844 0.83 ALDH1A1 (0.76) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL23465937 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL2088155 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL20959856 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL21753766 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL18411349 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL18525488 0.83 NPC1 (0.58) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240373749-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2024-11-07 US disclosed
US-12089494-B2 Organic electroluminescence element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-09-10 US disclosed
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2021-07-01 US disclosed
EP-3843167-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Kyushu University, National University Corporation (JP) 2021-06-30 EP disclosed
CN-112602206-A Organic electroluminescent element 国立大学法人九州大学 2021-04-02 CN disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240373749-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 ALDH1A1 157/4885NPC1 1759/4885RAB9A 1666/4885
US-12089494-B2 Organic electroluminescence element LEF1, EMC1, EEA1 ALDH1A1 157/4885NPC1 1759/4885RAB9A 1666/4885
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 ALDH1A1 157/4885NPC1 1759/4885RAB9A 1666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.