Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777441 | 0.77 | KMO (0.37) | JAK2JAK1KMOPPARALMNA | |
| SCHEMBL21769888 | 0.77 | KMO (0.37) | JAK2JAK1KMOPPARAGPR119 | |
| SCHEMBL6851712 | 0.77 | BRD4 (0.42) | ALDH1A1KMOPPARALMNAGPR119 | |
| SCHEMBL21387442 | 0.75 | KMO (0.33) | ALDH1A1KMOPPARAKAT6A | |
| SCHEMBL11712888 | 0.75 | ADORA2A (0.41) | ALDH1A1LMNAADORA2AADORA1MEN1 | |
| SCHEMBL11708534 | 0.73 | KDM4E (0.38) | ALDH1A1KMOLMNAGPR119ADORA2A | |
| SCHEMBL6878179 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMOPPARALMNAGPR119 | |
| SCHEMBL11708538 | 0.71 | ADORA2A (0.36) | ALDH1A1KMOLMNAADORA2AADORA1 | |
| SCHEMBL6878182 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMOPPARALMNAGPR119 | |
| SCHEMBL5649770 | 0.70 | RAB9A (0.46) | ALDH1A1LIMK1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |