SCHEMBL21752967

SCHEMBL21752967

Brc1ccc(Oc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
RAD52 P43351 3/20 0.49
RAB9A P51151 1/20 0.49
EPHX2 P34913 3/20 0.44
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
GFER P55789 1/20 0.43
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.40
CASP2 P42575 1/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
EPAS1 Q99814 1/20 0.38
MMP2 P08253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21756960 0.92 MEN1 (0.44) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL27845478 0.91 LMNA (0.61) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25709691 0.89 LMNA (0.63) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25709655 0.89 LMNA (0.63) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL2709413 0.89 LMNA (0.63) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL22815523 0.83 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25709677 0.83 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25907689 0.83 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25709659 0.83 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL27383409 0.83 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346549-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-11-13 US disclosed
CN-119954697-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2025-05-09 CN disclosed
CN-119930483-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2025-05-06 CN disclosed
US-20250084023-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-03-13 US disclosed
CN-118290322-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2024-07-05 CN disclosed
US-20240140895-A1 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2024-05-02 US disclosed
EP-3841095-A2 AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS Xeniopro GmbH (DE) 2021-06-30 EP disclosed
EP-3840834-A2 AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS Xeniopro GmbH (DE) 2021-06-30 EP disclosed
CN-112955439-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2021-06-11 CN disclosed
WO-2020039088-A2 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2020-02-27 WO disclosed
WO-2020039092-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084023-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LMNA 3829/4885ALDH1A1 810/4885MEN1 4486/4885
US-20250346549-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LMNA 3829/4885ALDH1A1 810/4885MEN1 4486/4885
US-20240140895-A1 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LMNA 3829/4885ALDH1A1 810/4885MEN1 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.