Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644184 | 0.72 | POLB (0.35) | POLBCYP3A4CYP2C9 | |
| SCHEMBL3317750 | 0.71 | CYP2D6 (0.41) | POLBMMP1MMP8 | |
| SCHEMBL16166384 | 0.70 | POLB (0.34) | POLBCYP3A4CYP2C9 | |
| SCHEMBL7718758 | 0.70 | POLB (0.38) | POLBCYP3A4CYP2C9 | |
| SCHEMBL11525181 | 0.70 | POLB (0.38) | POLBCYP3A4CYP2C9 | |
| SCHEMBL7339390 | 0.67 | — | — | |
| SCHEMBL28672492 | 0.67 | POLB (0.36) | POLBCYP3A4CYP2C9 | |
| SCHEMBL11797946 | 0.65 | HTT (0.40) | POLBCYP3A4CYP2C9 | |
| SCHEMBL7077560 | 0.65 | MEN1 (0.31) | — | |
| SCHEMBL28517815 | 0.64 | CA2 (0.37) | POLBCA2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |