Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753814 | 0.92 | SMN1; SMN2 (0.51) | ABCB1ABCC1SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21753816 | 0.90 | SIGMAR1 (0.53) | SIGMAR1GRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL21753822 | 0.89 | SMN1; SMN2 (0.54) | ABCB1ABCC1SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21753823 | 0.89 | MAPT (0.46) | GRM5SMN1; SMN2ALDH1A1TSHRFFAR1 | |
| SCHEMBL21753806 | 0.87 | GRM5 (0.44) | GRM5FFAR1MAPT | |
| SCHEMBL21753818 | 0.86 | GRM5 (0.47) | MMEGRM5 | |
| SCHEMBL21753827 | 0.85 | SMN1; SMN2 (0.42) | ABCB1ABCC1GRM5SMN1; SMN2ALDH1A1 | |
| SCHEMBL21753808 | 0.83 | GRM5 (0.47) | GRM5 | |
| SCHEMBL21756473 | 0.83 | ALDH1A1 (0.46) | GRM5ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL21753807 | 0.83 | NR1H4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040326-A1 | PHENYLACETIC ACID DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 가천대학교 산학협력단 | 2020-02-27 | — | — | WO | disclosed |